Kayne began his career in the mid-1960s as an analyst with Loeb, Rhodes & Co. in New York. Prior to forming Kayne Anderson, he was a principal of Cantor Fitzgerald & Co., Inc.
Kayne is a director of Glacier Water Services Inc. and the Jewish Community Foundation of Los Angeles. He also is a trustee of the UCLA Foundation.
In 1966, Kayne earned a B.S. degree in statistics from Stanford University. He received his MBA from UCLA Anderson School of Management in 1968.
